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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 9.7
Human Site: T725 Identified Species: 14.22
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 T725 L Q K Q R E V T D K R K E T Q
Chimpanzee Pan troglodytes XP_518055 1227 139177 T718 L Q K Q R E V T D K R K E T Q
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 A725 L Q K Q R E V A D K R K E T Q
Dog Lupus familis XP_549061 1234 139874 A726 L Q K Q Q E V A D K R K E T Q
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 A726 L Q K Q K E V A E K R K E T Q
Rat Rattus norvegicus Q7M6Z5 1394 158861 D823 V L Q K K Q Q D S K K L A S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 A731 L Q K Q R E A A D K R K E S Q
Frog Xenopus laevis Q91784 1226 138905 M728 L Q R Q K E A M E K R K D S Q
Zebra Danio Brachydanio rerio Q58G59 1363 154819 T818 L K Q K Q R D T A Q L A S L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 T331 S N Y N Y N E T L T T L R Y A
Honey Bee Apis mellifera XP_395595 1064 123475 E605 E L E K K I T E L R R K V T E
Nematode Worm Caenorhab. elegans P46873 699 78760 G246 Q S K T G A T G D R L K E A T
Sea Urchin Strong. purpuratus P46872 699 78679 V246 R V G K L H M V D L A G S E R
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 H592 G Q K L Q D I H A Q K L K T L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 S690 Q Q K I K Q E S E Q F R A W K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 L475 T K E E L I A L K D H D S K L
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 93.3 86.6 N.A. 80 6.6 N.A. N.A. 80 53.3 13.3 N.A. 6.6 20 26.6 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 53.3 N.A. N.A. 86.6 86.6 46.6 N.A. 6.6 53.3 33.3 26.6
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 20 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 60 N.A. N.A. 60 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 19 25 13 0 7 7 13 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 7 7 44 7 0 7 7 0 0 % D
% Glu: 7 0 13 7 0 44 13 7 19 0 0 0 44 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 7 0 7 0 7 0 0 7 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 7 0 7 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 7 0 13 7 0 0 0 0 0 0 0 0 % I
% Lys: 0 13 57 25 32 0 0 0 7 50 13 57 7 7 7 % K
% Leu: 50 13 0 7 13 0 0 7 13 7 13 19 0 7 19 % L
% Met: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 13 57 13 44 19 13 7 0 0 19 0 0 0 0 44 % Q
% Arg: 7 0 7 0 25 7 0 0 0 13 50 7 7 0 7 % R
% Ser: 7 7 0 0 0 0 0 7 7 0 0 0 19 19 7 % S
% Thr: 7 0 0 7 0 0 13 25 0 7 7 0 0 44 7 % T
% Val: 7 7 0 0 0 0 32 7 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 7 0 7 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _